John Murray, Jr. (b. 1758) was a nephew of John Murray. He lived at 335 Pearl Street and was a brewer with the firm Murray & Cunningham. He served as trustee of the City Dispensary and was treasurer of The Society for Promoting the Manumission of Slaves. He also was an early promoter of the free school system and a member of the Society of Friends. Murray worked with Thomas Eddy, another governor of the Society of the New York Hospital, to create an institution for the insane. The two men also served as the commissioners to carry a bill into effect that established a state prison.